djack, I appreciate your help in trying to explain, so please bear with me.
Let's assume water relief to keep it very simple protecting a positive displacement pump of 100gpm:
1) I agree 100psig must be the differential pressure, i.e. dP = 100psig because I know the start and end point pressures.
2) In contrast, let's say I have 100-ft of straight pipe (tweaking my example a bit) of 3-in, Sch 40 std wt steel pipe gives me a loss of 2.37 ft (or ~1psi) per Cameron. This says the piping alone will not bring you down to 0psig.
Am I fixing too many parameters, or something?
Having a pump capacity of 100 gpm has no relationship whatsoever with a differential pressure of 100 psi
d. Now you have 100 ft of pipe making too many 100's; hard to differentiate; your example is confusing and even nonsensical. The pressure at the discharge port of a PD pump will be anywhere from 0 psig to the mechanical limit of the pump and its driver. It will build to whatever pressure is needed to overcome discharge restrictions, up to the point where it stops working or breaks. If you removed all your discharge piping, the pressure would be atmospheric. It doesn't matter what the pump's nameplate says - that's just a maximum possible pressure. Add 100 ft of piping, and the pressure at the discharge port of the pump will be ~1 psig. Instead have 5000 ft of pipe and you're up to 50 psig. You get the idea. Nothing says that the pump discharge pressure WILL BE 100 psig. Hope that helps, and if you'd like to explore these concepts further, please strive to be precise and accurate. Those are becoming increasingly rare but remain absolutely essential in technical fields.